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Michael J Fossler Selected Research

8- chloro- 3- pentyl- 1H- purine- 2,6(3H,7H)- dione

10/2019A Randomized, Placebo-Controlled Trial to Assess the Effects of 8 Weeks of Administration of GSK256073, a Selective GPR109A Agonist, on High-Density Lipoprotein Cholesterol in Subjects With Dyslipidemia.

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Michael J Fossler Research Topics

Disease

7Acute Pain
12/2021 - 01/2017
6Pain (Aches)
01/2022 - 01/2017
4Postoperative Pain
06/2022 - 01/2017
4Vomiting
06/2022 - 01/2017
3Body Weight (Weight, Body)
01/2018 - 05/2002
2Sleepiness
06/2022 - 10/2021
2Respiratory Insufficiency (Respiratory Failure)
08/2020 - 01/2020
2Premature Birth (Birth, Premature)
01/2020 - 10/2015
2Chronic Kidney Failure (Chronic Renal Failure)
01/2020 - 09/2002
2Infections
01/2016 - 09/2012
1Torsades de Pointes (Torsade de Pointes)
12/2021
1Postoperative Nausea and Vomiting (PONV)
06/2021
1Migraine Disorders (Migraine)
01/2020
1Hyperalgesia
01/2020
1Flushing
10/2019
1Dyslipidemias (Dyslipidemia)
10/2019
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2019
1Nausea
01/2017
1Prostatic Hyperplasia (Benign Prostatic Hyperplasia)
05/2014
1Acute Coronary Syndrome
07/2013
1Chronic Hepatitis C
09/2012
1Insulin Resistance
09/2012
1BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
01/2009
1Neoplasms (Cancer)
01/2009
1Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor)
01/2009
1Leukemia
01/2009
1Myeloid Leukemia (Leukemia, Myelocytic)
01/2009
1Arthritis (Polyarthritis)
10/2007
1Rheumatoid Arthritis
10/2007
1Endotoxemia
10/2007
1Hypertension (High Blood Pressure)
06/2007
1Heart Failure
06/2007
1Peripheral Arterial Disease
12/2002

Drug/Important Bio-Agent (IBA)

11((3- methoxythiophen- 2- yl)methyl)((2- (9- (pyridin- 2- yl)- 6- oxaspiro(4.5)decan- 9- yl)ethyl))amineIBA
06/2022 - 01/2017
8Morphine (MS Contin)FDA LinkGeneric
06/2022 - 01/2017
6Opioid Analgesics (Opioids)IBA
06/2022 - 01/2020
6GTP-Binding Proteins (G-Protein)IBA
10/2021 - 01/2017
5Opioid Receptors (Opioid Receptor)IBA
12/2021 - 01/2018
4LigandsIBA
12/2021 - 01/2018
2Analgesics (Analgesic Drugs)IBA
01/2022 - 01/2020
2Tinzaparin (Innohep)FDA Link
09/2002 - 05/2002
1Oxycodone (Oxycontin)FDA LinkGeneric
01/2022
1Sodium Channels (Sodium Channel)IBA
12/2021
1Quinidine (Chinidin)FDA LinkGeneric
12/2021
1Ion Channels (Ion Channel)IBA
12/2021
1ArrestinIBA
10/2021
1AntiemeticsIBA
06/2021
1Oxytocin Receptors (Oxytocin Receptor)IBA
01/2020
1delta Opioid Receptors (delta Opioid Receptor)IBA
01/2020
1Nitroglycerin (Dynamite)FDA LinkGeneric
01/2020
1Oxytocin (Pitocin)FDA LinkGeneric
01/2020
1LipidsIBA
10/2019
1purineIBA
10/2019
1Fatty Acids (Saturated Fatty Acids)IBA
10/2019
18- chloro- 3- pentyl- 1H- purine- 2,6(3H,7H)- dioneIBA
10/2019
1Lipoproteins (Lipoprotein)IBA
10/2019
1HDL CholesterolIBA
10/2019
1Niacin (Nicotinic Acid)FDA LinkGeneric
10/2019
1G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA
10/2019
1Pemetrexed (MTA)FDA Link
01/2019
1Cytochrome P-450 CYP2D6 (CYP2D6)IBA
01/2018
1Tenofovir (Viread)FDA Link
01/2016
1CreatinineIBA
01/2016
1Emtricitabine (Emtriva)FDA Link
01/2016
1GSK221149AIBA
10/2015
1Tamsulosin (Flomax)FDA LinkGeneric
05/2014
1Dutasteride (Avodart)FDA Link
05/2014
16- (5- ((cyclopropylamino)carbonyl)- 3- fluoro- 2- methylphenyl)- N- (2,2- dimethylprpyl)- 3- pyridinecarboxamideIBA
07/2013
1p38 Mitogen-Activated Protein KinasesIBA
07/2013
1Ribavirin (Virazole)FDA LinkGeneric
09/2012
1Tyrosine Kinase InhibitorsIBA
01/2009
1Imatinib Mesylate (Gleevec)FDA Link
01/2009
1CollagenIBA
10/2007
1LipopolysaccharidesIBA
10/2007
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
10/2007
1Carvedilol (Coreg)FDA LinkGeneric
06/2007
1XV 459IBA
12/2002
1ProdrugsIBA
12/2002
1Platelet Membrane Glycoprotein IIbIBA
12/2002
1roxifibanIBA
12/2002
1Glycoproteins (Glycoprotein)IBA
12/2002
1Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA
09/2002

Therapy/Procedure

5Analgesia
12/2021 - 01/2017
2Abdominoplasty
06/2021 - 01/2017
1Patient-Controlled Analgesia (Analgesia, Patient Controlled)
01/2017
1Renal Dialysis (Hemodialysis)
09/2002